Josei/Seinen anime recommendations/anime with adult main characters?

Does anyone have any good anime recommendations where the main characters are adults and not in high school?

I've seen/am watching Nana, Tokyo Ghoul, Princess Jellyfish, Monster, Wotakoi and am planning to watch Berserk, Chihayafuru and Nodame Cantabile. I just wanted to see if there are any I should add to my list and if I'm missing any good ones. Josei recommendations would be especially appreciated.

Quote from blackjackdirecti

The Apothecary Diaries

Yeah I'm watching that right now, it's pretty cute though if I recall correctly they're 17 and not adults

Quote from n-o-v-a

master keaton

Ooh I've never heard of this, but apparently it's from the same creator as Monster so I'll add this to the list. Many thanks