Jejungwon (originally known as Gwanghyewon, or "House of Extended Grace"; the name was later changed to Jejungwon and then Severance Hospital after a major donor) was established in 1885 by Emperor Gojong at the suggestion of Horace Newton Allen, one of the newly arrived American medical missionaries. The first modern Western hospital in the Kingdom of Joseon, Jejungwon is documented as treating sick people regardless of their economic status, despite the hierarchical society of the era.
With Allen as its first hospital director, Jejungwon accepted 16 students for medical training. The series follows their training and careers.